The preparation of homogeneous monkey and human pituitary growth hormones.

Sulpiride-Induced Hyperprolactinemia in Mature Female Rats: Evidence for Alterations in The Reproductive System, Pituitary and Ovarian Hormones

The C-terminal amino acid sequence of growth hormones from human, monkey, whale, and sheep pituitary glands.

In another communication we have reported partial Nterminal amino acid sequences for growth hormones (somatotropins) of several species (1) ; these studies have indicated that whale, monkey, and human growth hormones are singlechain polypeptides at their N-terminus. To seek further evidence that these proteins are made up of single polypeptide chains, as well as to make additional comparisons w...

N-terminal amino acid analysis of growth hormones from human, monkey, whale, and beef pituitary glands.

The isolation of growth hormone (somatotropin) from human, monkey, and whale pituitary glands has recently been reported (l-3). Preliminary studies on the hormone proteins from these species have suggested that phenylalanine is their sole N-terminal amino acid residue (l-3), in contrast to the two N-terminal residues, alanine and phenylalanine, which have been reported for the bovine somatotrop...

Tissue-specific expression of squirrel monkey chorionic gonadotropin.

Pituitary gonadotropins LH and FSH play central roles in reproductive function. In Old World primates, LH stimulates ovulation in females and testosterone production in males. Recent studies have found that squirrel monkeys and other New World primates lack expression of LH in the pituitary. Instead, chorionic gonadotropin (CG), which is normally only expressed in the placenta of Old World prim...

An investigation on body weights, blood glucose levels and pituitary-gonadal axis hormones in diabetic and metformin-treated diabetic female rats

Diabetes is a metabolic disorder which affects whole body systems including reproductive system. Diabetes is also a contributing factor to infertility. Metformin is one of the most common drugs to control hyperglycemia. In this study, 36 adult Sprague-Dawley female rats (170-210 g) were divided into 3 groups (control, diabetic and diabetic-treated by metformin). In second and third groups, diab...